PCA3 test for prostate cancer

 

PCA3 is a new gene-based urine test for prostate cancer. It measures substances in the urine produced by prostate cancer cells. It is a simple test to perform which involves a brief prostate examination followed by a collection of urine.

The PCA3 test is sent to the lab for analysis and you'll be seen again in the clinic so your specialist can guide you through the results.

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Which test for prostate cancer: PCA3 or PSA?

PCA3 has some advantages over the standard PSA test:

  • It can avoid unnecessary prostate biopsies in patients who may have a raised PSA due to non-cancerous processes (i.e. it is more specific than PSA). This is because it is only produced by prostate cancer cells and not by increased prostate size.
  • It can provide extra reassurance that if you have had a negative prostate biopsy, prostate cancer has not been missed by the biopsy